Pioneering Cold Isotope Metallomics
Developing proprietary disease-modifying drugs designed to activate neurogenesis
Developing proprietary disease-modifying drugs designed to activate neurogenesis
We are leading the development of innovative therapies based on proprietary isotope-selective modulation ISM (tm) platform, designed to activate disease-modifying mechanisms that slow-down and potentially reverse neurodegeneration.
The metallome is intricately connected to other "omes" such as the genome, proteome, microbiome, and more, influencing and being influenced by those biological systems through its role in essential metal ion regulation and interactions.
The metallome encompasses the distribution of metal ions within tissues and celles, and is critical for a myriad of biological processes, including the synthesis of amino acids and proteins, maintaining charge balance and electrolyte function, ensuring DNA integrity and facilitating its repair, as well as playing a key role in structure, signaling, and stem cell functionality. Our drug candidates are designed to stimulate the fundamental biological activities of the metallome to re-establish a state of healthy homeostasis.
At the intersection of metallomics and drug development, our core expertise lies in Isotope-Selective Modulation ISM(tm). We harness the power of ISM(tm) platform to pioneer the treatments that not only target the underlying cascades of neurodegenerative diseases, but also promote the regeneration of neural cells and tissues, all while maintaining a steadfast commitment to patient safety.
Nomax emerged to revolutionize neurology with our distinctive scientific perspective on disease pathogenesis. Our approach is rooted in over ten years of research that delves deeper than molecular patterns, exploring the isotopic signatures at the atomic level within cells and tissues as part of metalloproteomics.
Heavy isotopes, when present in higher concentrations, can disrupt cellular functions and contribute to local and systemic inflammation and oxidative stress - two well-known harbingers of neuron death. Our isotope-selective modulation approach explores how metal isotopes impact biological functions and disease processes. By utilizing light cold isotopes, we are developing safe and effective drugs that engage multiple pathways for enhanced therapeutic outcomes in treating complex diseases and can be used in patients with chronic illnesses.
Unlike conventional medications that typically interact with their targets on a surface level, thereby managing symptoms rather than the root cause, our isotope-selective modulation, in conjunction with a multi-omic approach, empowers us to create drugs that holistically influence critical biological processes, ranging from protein synthesis and DNA repair to mitochondrial function.
Unhealthy aging, coupled with exposure to dietary and environmental factors hazards, can exacerbate the imbalance of metal isotopes, which becomes a driving force in a progress of pathology.
The medical use of stable light isotopes in various therapies is pivotal for their ability to cross the blood-brain barrier, enabling direct engagement with neurons in the brain, which is crucial for addressing neurological dysfunctions. The inherent safety profile of stable light isotopes in metallome highlights its transformative potential in the pharmaceutical industry, promising new era of treatments that are both more effective and clinically safe.
Metallomics integrates chemistry, biology, physics, and medicine focusing on the roles of metals in biological systems. It examines the metallome - the full spectrum of metals withing cells and organisms - using advanced mass spectrometry to uncover metal concentrations, distributions, and interactions. Metallome is crucial for understanding diseases linked to metal imbalances, such as neurodegenerative disorders, and for exploring the fundamental processes of life.
Founder, President & CSO
Chemistry & Business
Co-Founder & CEO
Biotech & Venture Capital
Co-Founder & CMO
Medicine & Molecular Biology
Co-Founder, VP & CFO
Nuclear Physics & Finance
Guided by our founders' proven track record in establishing successful enterprises, we have built a team of seasoned, mission-focused specialists who enhance our innovative approach and share our commitment to making a positive impact. We consistently explore and assess a broad range of available resources to support our business expansion and strengthen our operations.
175 Southwest 7th Street, Miami, Florida 33130, United States
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